dipose-derived stemcells



AAPE, an abbreviation for Advanced Adipose-derived stem cell Protein Extract, is a mixture of refined growth factor proteins that is extracted from human adipose-derived stem cells conditioned media. With its unique protein formula, AAPE maximizes the revitalizing effects of your skin and hair follicles.

AAPE for Hair

Stemcell Tech for increasing hair regrowth from the root care

AAPE for Skin

Stemcell Tech for ensuring skin cell regeneration and prompt restoration


비디오 재생


비디오 재생

AAPE Hair Brochure

AAPE Skin Brochure

AAPE Order Form


Produced at cGTP and sterile facility. Also passed in vitro, in vivo, animal and clinical tests.

CTFA Approved Registration date : 2006 / 9 / 13
Trade name : AAPE, INCI name : Advance Adipose-derived Protein Extracts.
Extracted Proteins from Conditioned Media of human Adipose-Derived Stem Cells.

Human donors. Adipose derived stem cells are cultured and during culturing under a special sterile condition, secret adipokines and useful growth factors and they are lyophilized and harvested at cGTP facility.

Natural composition of the various growth factors derived from ADSCs can provide the best biological activity. , Each growth factor has pharmacological effect but combination of growth factors may enhance the pharmacological action of single protein.

 AAPE increases collagen secretion and up-regulates mRNA expression of ECM proteins in HDFs(down regulation of MMP-1).
AAPE has anti-oxidant capacity as potent as 100M ascorbic acid.
AAPE increases SOD activity in HDFs.
AAPE induces GPx activity in HDFs.
Pre-treatment of AAPE reverses the tbOOH (free radical donor) that induces oxidative damage in HDFs.
AAPE inhibits melanin synthesis.
AAPE inhibits tyrosinase activity in a dose-dependent manner.
AAPE increases the migration of dermal fibroblasts

Concentration of Cytokines and Extracellular Matrix Proteins
PDGF44.41± 2.56 pg/ml
bDGF131.35± 30.31 pg/ml
KGF86.28± 20.33 pg/ml
TGF-β1103.33± 1.10 pg/ml
HGF670.94± 86.92 pg/ml
VEGF809.53± 95.98 pg/ml
Type | Collagen921.47± 49.65 pg/ml
Fibronectin1466.48± 460.21 pg/ml

Not derived from animals or plants. Exclusively patented conditioning and lyophilizing technique and science are applied to harvest high quality, sterile and purified adipokines and growth factors at cGTP facility.

 The first in 2006 and new version in 2012

For Skin every 3-6 weeks. about three treatments then 2 months, then 4 months.

We recommend every 3 weeks and 6 treatments for best result
For Hair , every 1 and a half to two months about 4-5 times

you can fide out more at our brochure

PRP, Stem Cells, Stromal Vascular Fractions (SVFs)

Yes, it is safe and effective to most of the patients as indicated and intended. With no allergic response or no side effects.

Available with fractional lasers or any skin ablation lasers, RF fractional laser and RF fractional micro-needling.

Available 0.25mm ~ .4 mm or deeper by physicians

Up to patients.
After 1.5 – 2 months x 1 or 2 sessions, patients feel some enhancement in scalp and hair thickness.
After 3-5 sessions, also hair numbers are increased.